Regulatory Update: Graded Motor Imagery Added to Exercise Protocol in Foot and Ankle Osteoarthritis Trial

By Dr. Hatem Rabeh · Published February 18, 2026 · Updated March 16, 2026

Publication date: February 19, 2026. This regulatory update describes a clinical trial entry that tests graded motor imagery as an adjunct to an exercise program for foot and ankle osteoarthritis. The record shows two behavioral interventions and lists a single sponsor. The trial is registered on ClinicalTrials.gov with identifier NCT07417436 and is currently marked as Recruiting. No outcome data are available in the registry at this time, and the entry underscores a willingness of individuals with foot or ankle osteoarthritis to participate in a non pharmacologic therapy study. The information is intended for regulatory and clinical teams seeking to monitor ongoing trials that may influence future care pathways. Details about endpoints or results are not yet reported in the registry; the emphasis remains on the design and status of the study.

What is the trial design?

The registry details a comparison that involves two behavioral intervention arms. Arm one uses an exercise program alone. Arm two adds graded motor imagery to the same exercise program. The study covers both foot and ankle osteoarthritis conditions. The sponsor identified in the record is Alanya Alaaddin Keykubat University. The design choice signals an interest in evaluating whether the addition of graded motor imagery to a standard exercise regimen can affect patient outcomes. Since no results are posted, the registry communicates a status of ongoing recruitment and ongoing data collection rather than completed findings.

What interventions are studied?

The study lists two behavioral interventions. The first is a structured exercise program. The second combines the exercise program with graded motor imagery. Both arms involve behavioral approaches rather than pharmacologic or device based therapies in the registry entry. The intention appears to be to observe feasibility and potential signals related to pain and function in people with foot or ankle osteoarthritis. No outcomes are reported yet and no safety issues are described in the registry.

Who is sponsoring and what is the status?

The sponsor identified for this trial is Alanya Alaaddin Keykubat University. The registry indicates the trial is currently recruiting, a status that implies ongoing participant enrollment and data collection. The absence of published results means stakeholders should anticipate updated entries as recruitment proceeds and as results become available for review on ClinicalTrials.gov.

What are the regulatory implications?

From a regulatory perspective this record highlights a non pharmacologic, behavior based intervention tested in a foot and ankle osteoarthritis population. If the study yields positive signals, insights could inform future patient care approaches and influence how such behavioral interventions are documented in regulatory submissions. Where applicable the MDR framework requires clear statements on the intended use, performance and safety of any tools or devices used in connection with graded motor imagery. The registry notes the source as sponsor information and does not provide clinical guidance. This update is aimed at regulatory teams monitoring ongoing trials and does not constitute medical advice.