On November 20, 2025, an important announcement was made regarding a clinical trial investigating the relationship between primary dysmenorrhea and two critical aspects of physical function: knee joint position sense and dynamic balance. The study, sponsored by Cairo University, has been listed as ‘not yet recruiting’ on ClinicalTrials.gov.
What does the study aim to examine?
The research explores the potential connections between primary dysmenorrhea—a clinical condition characterized by painful menstrual cramps—and its impact on proprioception in the knee joint and dynamic balance. While this condition is often associated with quality-of-life issues, little research to date has systematically evaluated how it might impair neuromuscular and balance control.
By focusing on proprioceptive feedback and physical stability, the study hopes to contribute actionable insights that could influence clinical interventions, rehabilitation programs, or device solutions targeted at women facing recurrent dysmenorrhea-related challenges.
What is primary dysmenorrhea?
Primary dysmenorrhea refers to painful menstrual periods without any underlying pelvic pathology. It is one of the most common gynecological complaints among women of reproductive age. Symptoms usually include cramping pain in the lower abdomen, which may extend to the back and thighs.
While the focus often remains on pain management, conditions such as dysmenorrhea may carry broader implications for motor control, potentially affecting activities that demand precision or balance. This study will be pivotal in investigating these underexplored aspects.
How will the study be conducted?
Although specific details on the methodology are not yet available, the trial’s sponsor, Cairo University, intends to evaluate females diagnosed with primary dysmenorrhea using standardized tools for assessing knee joint proprioception and dynamic balance.
Proprioception tests are expected to measure participants’ ability to sense and control joint movements, while dynamic balance assessments will likely focus on their ability to maintain stability during activity. Data obtained from this study can deepen understanding of how menstrual pain-related dysfunction influences mechanical and sensory systems.
The trial’s status, as of November 2025, is ‘not yet recruiting,’ and updates may be forthcoming regarding participant inclusion and practical applications for the results.
Frequently Asked Questions
1. Who can participate in this clinical trial?
Although the recruitment phase has not begun, eligibility criteria will likely require participants to be females diagnosed with primary dysmenorrhea. Specific inclusion and exclusion criteria will provide clarity once recruitment begins.
2. How can this study benefit patients?
Insights from this research may improve interventions addressing sensory and balance impairments linked to dysmenorrhea. This could include developing tailored exercises or device innovations that offer long-term benefits.
3. Where can updates about the trial be found?
Interested parties can monitor updates via ClinicalTrials.gov or consult the trial’s sponsor, Cairo University, to stay informed about participant enrollment and preliminary outcomes.
Key takeaways and implications
This study highlights the need to broaden perspectives on the physiological effects of primary dysmenorrhea. By linking proprioceptive and balance functions to menstrual health, it ushers in a multidisciplinary approach to diagnostics and treatment. Researchers, clinicians, and regulatory teams will closely follow its findings for their potential to shape interventions or influence regulatory considerations in pain management and rehabilitation solutions.
Disclaimer
This article is for informational purposes only. It is not legal advice and should not be interpreted as such. Consult regulatory or clinical experts for specific guidance.
Where to find more information
For full information about the announcement, see the link below.
https://clinicaltrials.gov/study/NCT07239232?term=medical+device