Publication Date: November 22, 2025
A new randomized clinical trial sponsored by Cairo University aims to evaluate how different dental implant thread designs affect primary stability in the posterior maxilla when using an advanced osseodensification technique. This study will provide critical insights into the performance of knife threads compared to double threads for implant stability, a key consideration for clinical and regulatory professionals.
In this article:
- Impact of thread design on implant stability
- How will the trial be conducted?
- Why is this study important?
- Frequently asked questions
- Key takeaways for clinical teams
- Disclaimer
- Announcement and link
Impact of thread design on implant stability
Dental implant primary stability is crucial for successful osseointegration and long-term functionality. This study investigates the differences between knife thread and double thread implants in the posterior maxilla, an area challenging for osseointegration due to lower bone density.
Knife threads are engineered to cut into the bone more efficiently, potentially offering higher initial stability. Double threads, by contrast, are designed for improved mechanical anchorage, which could reduce micromovement during healing. The trial will measure stability outcomes to compare these designs objectively.
How will the trial be conducted?
The study methodology involves a randomized clinical trial format with rigorous controls. Eligible participants will receive implants using the osseodensification technique, which compacts and densifies surrounding bone during drilling. This method is known to improve implant stability, particularly in areas with low bone density.
Two groups will be formed: one receiving knife-thread implants and the other double-thread implants. Primary stability will be assessed using standardized methods immediately post-surgery, offering detailed performance data for regulatory review.
Why is this study important?
Clinical teams, manufacturers, and regulators are keenly aware of the challenges in establishing reliable stability in low bone-density regions. This trial addresses a critical knowledge gap, offering robust comparative data on thread design performance with the osseodensification technique.
Furthermore, trial findings could influence dental implant design standards and regulatory compliance requirements. By enhancing understanding of how thread designs interact with advanced surgical techniques, the industry could achieve better patient outcomes and compliance with Medical Device Regulation (MDR) standards.
Frequently asked questions
1. Who is conducting the trial?
The trial is sponsored by Cairo University.
2. Are participants being recruited now?
No, the trial is not yet recruiting at this time.
3. What devices will be used?
Both groups will use dental implants, with comparison between knife-thread and double-thread designs.
Key takeaways for clinical teams
The upcoming trial represents a significant opportunity to assess the effect of implant thread designs on stability when using innovative surgical techniques. The findings could improve implant design, inform surgical best practices, and guide regulatory standards. Professionals should monitor this study for actionable insights affecting their field.
Disclaimer
The information in this article is intended for clinical and regulatory professionals. It does not constitute legal advice and should be used alongside official regulatory guidelines.
Announcement and link
For full information about the announcement, see the link below.
https://clinicaltrials.gov/study/NCT07242716?term=medical+device