Publication date context: February 15, 2026. A ClinicalTrials.gov record for NCT07408570 outlines a study that examines frequency dependent soleus reflex modulation during whole body vibration in healthy adults. Sponsored by Istanbul Physical Medicine Rehabilitation Training and Research Hospital, the trial is listed as enrolling by invitation. The entry identifies whole body vibration as the intervention and healthy adult as the condition. This regulatory minded update summarizes what is publicly available while noting the current limits of the posted data and the formal status for device use in this research context.
In this article
- What is the study design and scope?
- Who participates?
- When is this study taking place and what is the status?
- What are the regulatory implications for devices used in research?
- What safety considerations are noted?
- Frequently asked questions
- What is the bottom line for researchers and device makers?
What is the study design and scope?
The posting describes a research effort in which a vibration device is used to study neuromuscular responses. The target outcome is frequency dependent modulation of the soleus reflex, a known contributor to standing balance and movement control. The study lists healthy adults as the condition and whole body vibration as the intervention. Enrollment is indicated as by invitation and the sponsor is Istanbul Physical Medicine Rehabilitation Training and Research Hospital. No regulatory clearance or new indication is stated in the posting; the document frames the work as a research activity rather than a clinical intervention. This framing aligns with typical university or hospital based investigations that aim to characterize device performance and physiological responses in a controlled setting.
Who participates and who is eligible?
Eligible participants are described as healthy adults. Enrollment is by invitation, meaning potential participants are contacted through a sponsor or site rather than open enrollment. The sponsor is a Turkish hospital, which implies a site based in that region. The posting does not provide additional inclusion or exclusion criteria in the text presented. For regulators and manufacturers, this signals a restricted access approach common in early phase studies where safety and initial response profiles are explored before broader recruitment.
When is this study taking place and what is the status?
The ClinicalTrials.gov entry is timestamped February 15, 2026 and lists enrollment by invitation. This indicates a early stage activity with a limited participant pool. The posting does not share milestones or results beyond the current description. For device developers, this means data generation may be limited to initial neuromuscular observations rather than definitive clinical outcomes.
What are the regulatory implications for devices used in this trial?
The entry shows a vibration device used to study neuromuscular responses in a research setting. There is no mention of regulatory clearance or a new device indication. For device makers and regulators, this kind of listing underscores the need to document device performance, safety measures, and study design when assessing devices used in research. The description suggests a research oriented use of the device rather than a clinical approval. In MDR terms this aligns with an intended use statement that is limited to research and data collection, and it implies that any subsequent regulatory actions would rely on the strength and relevance of the generated evidence.
What safety considerations are noted?
The posted text identifies healthy adult participants but does not provide safety results or an explicit risk assessment. Absence of safety data means readers should not draw conclusions about risk from the posted entry alone. Standard research procedures and oversight would apply in practice. Regulators would expect ongoing monitoring, adverse event reporting, and a risk management plan if this device is involved in clinical population studies or if future indications are pursued.
Frequently asked questions
- 1. What is studied
The trial examines frequency dependent soleus reflex modulation during whole body vibration in healthy adults. - 2. Who may participate
Healthy adults are eligible; enrollment is by invitation as described in the listing. - 3. Where is it conducted
The sponsor is Istanbul Physical Medicine Rehabilitation Training and Research Hospital; location is not specified beyond the sponsor. - 4. What is the trial status
Enrollment by invitation is listed; no further milestones are described. - 5. What is the intended use of the device in this study
The device provides whole body vibration as part of a research protocol to study neuromuscular responses. - 6. How does this relate to regulatory decisions
There is no stated regulatory clearance or new indication in the posting; it is a research listing that may inform future regulatory documentation.
Bottom line for researchers and device makers
The listing illustrates ongoing inquiry into how vibration frequency influences reflex pathways during a classic motor task. For device makers this work can inform how performance is characterized and how safety data is reported in future studies. Regulators will want to monitor study status and ensure that research devices are used in compliance with applicable standards. The sponsor and site information point to where oversight will occur during the study.
Information in this article is intended for clinical, quality and regulatory professionals. It is not legal advice. It reflects the publicly available record and does not establish or imply regulatory clearance.
https://clinicaltrials.gov/study/NCT07408570?term=medical+device